Marie Kyselková studied to be a nurse, on the side she performed as a singer and dancer with different ensembles. She also worked as a model for both runway shows as well as a photomodel in Prague. At one of those events she was discovered by Jiří Sequens who gave her a small role in one of his movies in 1955. Kyselková was a regular at the Divadlo S. K. Neumanna theatre in Libeň, a part of Prague. In 1959 she landed the role of Princess Lada in the movie the 'Princess with the Golden Star' - while filming she